MULTI ORGAN MODELING
 
The vaccines save lives by preventing diseases in both human and animals, e.g., polio, smallpox, measles, tetanus and rabies. Live attenuated vaccines are generated by disabling the virulent properties of viruses so that a broad immune response can be generated e.g., Yellow fever, measles, mumps and rubella etc. The potential of any vaccine strategy can only be proven by establishing safety, potency and consistent manufacturing processes. The present state of art relies primarily on animal testing to study neurovirulence, immunogenicity and viscerotropism as per current regulatory guidelines (WHO Annex 5, 2013). Stemnovate was awarded NC3Rs grant for implementation of 3Rs (Replacement,Reduction and Refinement). The grant challenge was sponsored by Sanofi for developing a model system for Yellow fever vaccination studies.
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Platform Features
  1. World’s first commercial biobank for human iPS cells with complete genotype information.
  2. Multicellular modelling with novel tissue engineering.
  3. Viral infectivity modelling.
  4. Neuro-invasive, viscerotropic and immunogenicity studies.
  5. Complete gene expression profiling with transcriptomics. 
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Platform Compliance
  1. Regulatory compliance for biobanking.
  2. Complete consent for commercial use.
  3. Biosafety Level 2 laboratory for virus handling.
  4. Schedule 5 notification.
Products

Induced Pluripotent stem cell lines

Human & Multispecies Primary cells

Cell culture & analysis package

Services

Cell Reprogramming

Cell Differentiation

Application Development
Data

Pharmacogenomic Data 

Single Nucleotide Polymorphism

Transcriptomics

Pharmacokinetic/Pharmacodynamic Data
Device

Microphysiological systems

Microfluidic design, prototyping and manufacturing

Biosensing and Automation

Our clients say

You are doing some amazing and important work at Stemnovate, we are happy to be associated with your project.“

Volunteer
Volunteer for blood donation for liver research

Thank you for your presentations, they were really great and stimulating. I am very happy we met and that we could get the cells in culture!“

Academic Institution
University of Bern

CASE STUDIES & Partnership

Slippery Liquid-Infused Porous Surfaces: Partnering for Micro-fluidics Smart engineering

Prof Ciro Semprebon will be working in partnership with Stemnovate on the prestigious EPSRC grant project for advancing SLIPS technology.

04.05.2020
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Partnering for European Space Agency Microgravity Application Promotion Programme

Stemnovate has partnered with multinational collaborators on a project coordinated by MEDES Institute of space medicine and physiology. 

25.10.2019
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