Our mission is to accelerate drug discovery from decades to years and from months to days.
Building the future, caring for both human and animal lives. We are StemnovateTM .

HOW IT WORKS

How it works
Multiorgan solution

In vitro Absorption, distribution, metabolism and excretion studies can be conducted on tissues showing multicellular interactions in microphysiological systems.

Computational modelling & Big Data

The multiparametric data obtained from cell studies, assays, protein and gene expression and imaging is used for data analysis and predictive modelling of drug response.

Biosensing

The quantitative data is obtained through biosensors for microenvironment changes and physiological parameter analysis.

Drug Interaction studies

Cytochrome P450 studies are complimented with metabolism assays, expression profiling and transcriptomic analysis. A comprehensive data to understand the mechanistic of action or toxicity.

Cell based assays

In-depth studies for cell proliferation, apoptosis, receptors & transporters.

3D printing prototyping manufacturing

Microfluidic device development involves CAD design, 3D printing, prototyping following by application optimisation and manufacturing.

Pharmacogenetics

Pharmacogenetics allows the study of the genetic variation due to ethnicity and gender that affects their response or adverse reaction to
medicines or xenobiotics.
Stemnovate has diverse bank of IPS lines that represent the human variability for pharmacogenetics studies.

Reduces Animal Testing Veterinary Research and Development

Our multispecies cellular models allow in vitro studies for mechanism of action, transporters and signalling pathways. This reduced animal testing while the models benefit veterinary drug development and disease modelling.

Drug metabolism Cytochrome P450 studies

Cytochromes P450 (CYPs) are the main enzymes involved in drug metabolism. These show huge expression variability among humans. We study CYP inhibition, induction, expression and polymorphism.

Multicellular Modelling Tissue engineering

Tissue consists of specialised cells functioning while uniquely organised. We simulate this organisation for microphysiological studies. Eg, Liver tissue consists of hepatocytes, stellate and Kupffer cells.

Partnership

Partnerships

We have global partnerships that include top tier pharmaceutical companies and world-renowned academia. As a result, we have successfully delivered projects that incorporate innovation and integration of advanced microengineering and cellular technologies.
We have industrial partnerships on several PhD studentships with the National Physical Laboratory, the University of Edinburgh, the University of Northumbria, and the Babraham Institute, to name a few.
Stemnovate is certified as an ISO 9001: 2015 company. We have an experienced team of Phds and Postdocs from top institutes across the world, and hence are well equipped to overcome challenges in research and development.

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