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Important Notes
By sourcing all of our products from the United Kingdom through informed consent for commercial use, we ensure that we provide you with the highest quality goods. We take pride in our commitment to ethical and responsible practices and are confident that you will be satisfied with the products you receive.
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Features
Stemnovate offers high-quality human iPSC Cell Lines for researchers and scientists. They use these iPSC cell lines in disease modelling and other stem cell research.
The iPS lines show stable expression of core pluripotency genes such as NANOG, TRA 1-60, OCT4, SOX2, LIN28 over several passages and characterisation includes immunochemistry qPCR analyses.
The feeder-free and serum-free conditions help cells to maintain in pluripotent state and long-term storage while frozen below -80ºC or in liquid Nitrogen. Stemnovate has whole-genome transcriptomics and the genotype information for all iPSC lines. In other words, bioinformatic evaluation includes comparative studies to three human embryonic stem cell lines.
Stemnovate iPSCs form embryoid bodies and differentiate into derivatives of the three germ layers in vitro. As a result, IPS on differentiation into embryoid bodies express ECTODERM MESODERM and ENDODERM Markers.
Applications
Stemnovate's induced pluripotent cells (iPSCs) are formed by reprogramming somatic cells such as skin (fibroblasts and keratinocytes) or blood (PBMNCs - peripheral blood mononuclear cells). Therefore, iPSCs represent a unique and ethical tool for modelling disease and organ toxicity, with enormous potential for drug discovery and cellular therapies.
The non-integrating methods results in stable IPS line generation with high efficiency and reproducibility compared to other viral reprogramming methods. The ability to expand pluripotent cells in-vitro and subject them to direct differentiation to produce specific cell types is crucial to developing cell based therapies to replace or restore tissue.
Compliance
Stemnovate holds a commercial license from IPS Academia Japan for which Prof. Yamanaka and Prof. Gurdon received the Noble prize in 2012 for reprogramming technology.
Stemnovate human iPS cell lines are tested negative for HIV-1. HIV-2, Hepatitis-A, Hepatitis-B, Bacteria and Microplasma.
Disclaimer
Stemnovate does not sell or generate human embryonic stem cell lines. The pre-established HES lines are for research and development purposes only.